Aim: This paper concerns orthodontic alignment of the maxillary lateral incisor on the cleft side of a lip and alveolar cleft patient after a secondary autogenous cancellous bone graft at the late stage of mixed dentition. Subject and Treatment: The patient was a Japanese girl 9 years 7 months of age who presented at the authors’ clinic with a repaired lip and alveolar cleft and an incisor crossbite. At 12 years of age, a secondary bone graft of the alveolar ridge was performed using bone harvested from the iliac crest. At 14 years 7 months of age, a conventional fixed appliance was placed. Results: The lateral incisor on the cleft side was brought to the line of occlusion by orthodontic alignment. A Class I molar relationship on both sides and a satisfactory facial profile were achieved. After a 2-year retention period, the occlusion and esthetics were maintained. Five years after grafting, however, a satisfactory bone level was not achieved due to positioning of the root of the lateral incisor, which was not completely upright in the bone graft area due to root tipping. World J Orthod 2009; 10:67–75.