Home Subscription Services

World Journal of Orthodontics
WJO Home Page
About the Editor
Editorial Board
Reprints / Articles
Quintessence Publishing: Journals: ORTHODONTICS
The Art and Practice of Dentofacial Enhancement

Formerly World Journal of Orthodontics

Edited by
Rafi Romano, DMD, MSc (Editor-in-Chief)

ISSN 2160-2999 (print) / ISSN 2160-3006 (online)

Visit the ORTHODONTICS: The Art and Practice of Dentofacial Enhancement Facebook page

Winter 2008
Volume 9 , Issue 4

Share Abstract:

Tooth agenesis in a family and homozygous PAX9 mutation in exon 3: A case report

Katherine Kula, MS, DMD, MS/Justin Trimmell, DDS, MS Resident/Yongbo Lu, PhD Patrick Briscoe, DDS, MS Resident/Jian Q. Feng, MD, PhD

Page: 412
PMID: 19641755

Aim: To determine if the variable expression of tooth agenesis in a family whose members all presented with multiple and variable tooth agenesis is related to a mutation of the PAX9 gene. Methods: The family was examined and its histories recorded. A buccal cheek swab was used to isolate DNA and sequencing of the PAX9 gene was performed. Results: All family members had a homozygous point mutation at the 718 position (G to C) in exon 3 (a nonpaired domain) of PAX9. Conclusion: The variable expression of tooth agenesis in this family suggests that clinicians should carefully examine all members of a family in which tooth agenesis is identified. World J Orthod 2008;9:412.e5561.

Full Text PDF File | Order Article


Get Adobe Reader
Adobe Acrobat Reader is required to view PDF files.
This is a free program available from the Adobe web site.
Follow the download directions on the Adobe web site
to get your copy of Adobe Acrobat Reader.
  © 2022 Quintessence Publishing Co Inc

Home | Subscription Services | Books | Journals | Multimedia | Events | Blog
Terms of Use | Privacy Policy | About Us | Contact Us | Advertising | Help | Sitemap | Catalog