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Quintessence Publishing: Journals: QI
Quintessence International

Edited by Eli Eliav

ISSN 0033-6572 (print) • ISSN 1936-7163 (online)

Publication:
October 2010
Volume 41 , Issue 9

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The Influence Of Saliva On The Dissolution Of Calcium Fluoride After Application Of Different Fluoride Gels In Vitro

Elmar Hellwig, Dr Med Dent, DDS, PhD/Olga Polydorou, Dr Med Dent/Adrian Lussi, Dr Med Dent/Andrej M. Kielbassa, Dr Med Dent/Markus J. Altenburger, Dr Med Dent

Pages: 773-777
PMID: 20806102

Objective: To determine the formation and dissolution of calcium fluoride on the enamel surface after application of two fluoride gel–saliva mixtures. Method and Materials: From each of 80 bovine incisors, two enamel specimens were prepared and subjected to two different treatment procedures. In group 1, 80 specimens were treated with a mixture of an amine fluoride gel (1.25% F-; pH 5.2; 5 minutes) and human saliva. In group 2, 80 enamel blocks were subjected to a mixture of sodium fluoride gel (1.25% F; pH 5.5; 5 minutes) and human saliva. Subsequent to fluoride treatment, 40 specimens from each group were stored in human saliva and sterile water, respectively. Ten specimens were removed after each of 1 hour, 24 hours, 2 days, and 5 days and analyzed according to potassium hydroxide–soluble fluoride. Results: Application of amine fluoride gel resulted in a higher amount of potassium hydroxide–soluble fluoride than did sodium fluoride gel 1 hour after application. Saliva exerted an inhibitory effect according to the dissolution rate of calcium fluoride. However, after 5 days, more than 90% of the precipitated calcium fluoride was dissolved in the amine fluoride group, and almost all potassium hydroxide–soluble fluoride was lost in the sodium fluoride group. Calcium fluoride apparently dissolves rapidly, even at almost neutral pH. Conclusion: Considering the limitations of an in vitro study, it is concluded that highly concentrated fluoride gels should be applied at an adequate frequency to reestablish a calcium fluoride–like layer. (Quintessence Int 2010;41:773-777)

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