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Quintessence Publishing: Journals: QI
Quintessence International

Edited by Eli Eliav

ISSN 0033-6572 (print) • ISSN 1936-7163 (online)

November/December 2009
Volume 40 , Issue 10

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Odontogenic Carcinoma Differentiation Into Rhabdomyosarcoma: Report of a Rare Case

King Kim, DMD/Ines Velez, DDS, MS/Steven I. Kaltman, DMD, MD/Eustorgio Lopez, DMD, MD/Diane Stern, DDS

Pages: 837–842
PMID: 19898715

To the authors’ knowledge, this is the first reported case of an odontogenic carcinoma with documented skeletal muscle differentiation (rhabdomyosarcoma). The histology and clinical features of this aggressive odontogenic neoplasm are described. Within the English-language literature, only 2 cases are reported of an odontogenic tumor with muscle differentiation: a benign odontogenic tumor (ameloblastoma) with differentiation into a rhabdomyosarcoma and an odontogenic sarcoma with smooth-muscle differentiation. The general practitioner should be aware that odontogenic lesions may be malignant, even though this is extremely rare, and all tissue removed from the oral cavity should be submitted for biopsy. (Quintessence Int 2009;40:837–842)

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