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Quintessence Publishing: Journals: QI
Quintessence International

Edited by Eli Eliav

ISSN 0033-6572 (print) • ISSN 1936-7163 (online)

Publication:
June 1997
Volume 28 , Issue 6

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Use of tranexamic acid mouthwash to prevent postoperative bleding in oral surgery patients on oral anticagulant medication

Gaspar/Brenner/Ardekian/Peled/Laufer

Pages: 375-379
PMID: 9477900

The clinical hemostatic effect of tranexamic acid mouthwash after oral surgery was evaluated in 47 patients receiving oral anticoagulant therapy. Surgery was performed after the anticoagulant medication was recued in 15 patients (control group) and with no change in anticoagulant therapy in 32 patients (test group). The only st atistical difference between the two treatment groups at baseline was the level of anticoagulation, which was significantly higher in the test group. There was no significant difference between the two treatment groups in the incidence of bleeding after oral surgery. The results indicated that a combination of local antifibrinolytic therapy and a local hemostatic agent is effective in preventing postoperative bleeding after oral surgery in patients treated with anticoagulants.

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