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Quintessence Publishing: Journals: QI
Quintessence International

Edited by Eli Eliav

ISSN 0033-6572 (print) • ISSN 1936-7163 (online)

May 1997
Volume 28 , Issue 5

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A clinical assessment of the effectiveness of a mouthwash based on triclosan and on Zea mays L used as supplements to brushing


Pages: 329-335
PMID: 9452696

The effectiveness of a mouthwash based on triclosan in combatting plaque and gingivitis was compared with a mouthwash based on nonsaponifiable maize germ (Zea mays L). Both were used to supplement conventional mechanical oral hygiene. The study was carried out under double-blind conditions with a negative control (a placebo) and a positive control (a mouthwash based on chlorhexidine). After a period of 14 days to allow the Plaque Index and Gingival Index to standardize, the 43 subjects who formed the sample were examined weekly for 3 weeks. During the study, five subjects were excluded because they did not meet criteria for selection for the study. Although the mouthwash based on triclosan reduced the Plaque Index by 7.3% in comparison with the placebo negative control (a less marked effect than that of chlorhexidine, which achieved an 8.43% reduction), it had scarcely any effect on th e Gingival Index. The mouthwash based on Zea mays L had no beneficial action on the Plaque Index, which increased slightly, but it led to an improvement in the Gingival Index (7.17% in comparison with the placebo).

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