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Quintessence Publishing: Journals: QI
Quintessence International

Edited by Eli Eliav

ISSN 0033-6572 (print) • ISSN 1936-7163 (online)

January 2009
Volume 40 , Issue 1

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Primary oral malignant melanoma—A case report and review of the literature

Shailesh M. Gondivkar, MDS/Atul Indurkar, MDS/Shirish Degwekar, MDS/Rahul Bhowate, MDS

Pages: 41–46
PMID: 19159022

Malignant melanoma is a neoplasm of melanocytic origin that arises from a benign melanocytic lesion or de novo from melanocytes within otherwise normal mucosa or skin. Melanoma arising from the mucosal surfaces of the head and neck is a very rare disease and is considered among the most deadly of all human neoplasms. Although it comprises 1.3% of all cancers, malignant melanoma of the oral cavity accounts for only 0.2% to 8.0% of all reported melanomas. Because most mucosal melanotic lesions are painless in their early stages, the diagnosis is unfortunately often delayed until symptoms resulting from ulceration or growth are noted. Oral malignant melanoma has an extremely poor prognosis. For prevention of oral mucosal melanomas, any solitary pigmentation that has no obvious explanation should be always biopsied. The case of a 40-year-old man with primary malignant melanoma of the maxillary gingiva is reported. (Quintessence Int 2009;40:41–46)

Key words: melanocytes, oral malignant melanoma, pigmented areas

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