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Quintessence Publishing: Journals: QI
Quintessence International

Edited by Eli Eliav

ISSN 0033-6572 (print) • ISSN 1936-7163 (online)

Publication:
November 2008
Volume 39 , Issue 10

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In vitro reduction of mutans streptococci by means of ozone gas application

Ana Castillo, MD, PhD/Pablo Galindo-Moreno, DDS, PhD/Gustavo Avila, DDS, PhD/Mariano Valderrama, PhD/José Liébana, MD/Pilar Baca, DMD

Pages: 827–831
PMID: 19093059

Objective: To evaluate, in vitro, the antimicrobial effect of ozone gas on strains of reference mutans streptococci and strains isolated from children at a high risk of developing caries. Method and Materials: A series of dilutions was obtained from a total of 41 strains, and the effect of ozone was determined for applications of 10, 20, and 40 seconds, as well as a control, in terms of the reduction of viable bacteria. Results: Ozone application for 10 and 20 seconds produced a significant reduction in the number of bacteria, inversely proportional to the bacterial concentration. When exposure lasted 40 seconds, no viable bacteria were obtained. Conclusions: Both time of application and initial bacterial concentration bear an influence on the antimicrobial effect of ozone on mutans streptococci. (Quintessence Int 2008;39:827–831)

Key words: antimicrobial agents, caries, caries therapy, in vitro study, mutans streptococci, ozone

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