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Quintessence Publishing: Journals: QI
Quintessence International

Edited by Eli Eliav

ISSN 0033-6572 (print) • ISSN 1936-7163 (online)

February 2008
Volume 39 , Issue 2

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Effectiveness of 2-year application of school-based chlorhexidine varnish, sodium fluoride gel, and dental health education programs in high-risk adolescents

Nazan Kocatas Ersin, PhD, DDS/Ece Eden, DDS, PhD/Nesrin Eronat, PhD, DDS/Fusun Irem Totu, PhD/Mustafa Ates, PhD

PMID: 18560640

Objective: To compare the caries preventive effects of 2-year application of school-based chlorhexidine varnish, sodium fluoride gel, and dental health education programs among a high-risk group of 11- to 13-year-olds with low caries activity. Method and Materials: A total of 149 subjects who had previous caries experience in the primary dentition and Streptococcus mutans levels higher than 105 at baseline with 0 DMFS index were selected for this randomized clinical trial. Subjects were allocated to one of 3 groups for treatment with chlorhexidine varnish (n = 50), sodium fluoride gel (n = 50), or a dental health education program (n = 49), which were repeated throughout the 2-year study. The outcomes examined at the end of the study were the caries increment (DMFS index), dental plaque scores, and salivary S mutans counts. Results: The subjects in the education group showed a significant increase in the salivary levels of S mutans in comparison with the other groups (P = .004), but there was no significant difference among the groups in the caries increment after 2 years, with mean DMFS SD as 0.95 1.33, 0.88 1.47, and 1.05 2.01 in the chlorhexidine varnish, sodium fluoride gel, and education groups, respectively. There were also no significant differences in the pre- and posttreatment plaque scores between the groups. Conclusion: Although all 3 preventive programs in this high-caries-risk group of children with low caries activity resulted in similar plaque and caries values after 2 years, longer follow-up studies are needed to clarify the effect of reduction in S mutans growth by chemotherapeutic agents in caries incidence. (Quintessence Int 2008;39:178.e4551)

Key words: caries, chlorhexidine, education, fluoride, Streptococcus mutans

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