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Quintessence Publishing: Journals: QI
Quintessence International

Edited by Eli Eliav

ISSN 0033-6572 (print) • ISSN 1936-7163 (online)

March 2006
Volume 37 , Issue 3

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Periodontal manifestation of Langerhans’ cell histiocytosis in a young man: Case report with a 24-month follow-up

Filip Klein, Dr med dent / Diana Krigar, Dr med dent / Detlev Petzoldt, Prof Dr med / Peter Eickholz, Prof Dr med dent

Pages: 175–182
PMID: 16536144

A 25-year-old male patient with skin lesions of Langerhans’ cell histiocytosis (LCH) was referred for periodontal treatment because of bilateral severely inflamed ulcerative periodontal lesions at the mandibular second premolar and first molar. On the left side, significant bone loss was revealed. Anti-infectious and surgical periodontal therapy resulted in significant probing pocket depth reduction and clinical attachment gains that were maintained for up to 24 months after surgery. Biopsies were taken during periodontal surgery. Immunohistochemical staining revealed that the periodontal lesions were uncommon periodontal manifestations of LCH. Reports of oral manifestation of LCH and treatment methods are reviewed.
(Quintessence Int 2006;37:175–182)

Key words: eosinophilic granuloma, histiocytosis X, Langerhans’ cell histiocytosis, periodontal disease, periodontal manifestation of systemic disease

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