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Quintessence Publishing: Journals: QI
Quintessence International

Edited by Eli Eliav

ISSN 0033-6572 (print) • ISSN 1936-7163 (online)

May 2014
Volume 45 , Issue 5

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Bilateral necrotizing sialometaplasia of the hard palate in a patient with bulimia: A case report and review of the literature

Janner, Simone F.M. / Suter, Valerie G.A. / Altermatt, Hans Jörg / Reichart, Peter A. / Bornstein, Michael M.

Pages: 431-437
PMID: 24634907
DOI: 10.3290/j.qi.a31543

Necrotizing sialometaplasia (NS) is a rare and benign lesion that mostly affects the posterior hard palate. Its importance resides in its clinical and microscopic characteristics, which can closely mimic malignant neoplasias, in particular oral squamous cell carcinoma and mucoepidermoid carcinoma. Accurate histopathologic evaluation of an incisional biopsy is considered as the diagnostic gold standard. NS lesions heal spontaneously within weeks, and no further treatment is necessary. We report a case of a bilateral palatal NS in a 22-yearold woman with bulimia, where an incisional biopsy confirmed the clinical diagnosis. The different clinical stages of the lesions from onset to resolution and the possible etiologic factors are described in detail, as well as a discussion of the differential diagnoses of palatal ulcers. When taking a biopsy from suspicious oral lesions, care has to be taken that an appropriate tissue sample is harvested, and the histopathologic analysis is performed by an experienced pathologist to establish a correct diagnosis. Keywords: biopsy, bulimia nervosa, eating disorders, minor salivary glands, necrotizing sialometaplasia, oral ulcers

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