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Quintessence Publishing: Journals: QI
Quintessence International

Edited by Eli Eliav

ISSN 0033-6572 (print) • ISSN 1936-7163 (online)

Publication:
June 2012
Volume 43 , Issue 6

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Increased gingival blood vessel density in SLE patients

Giuseppe Alessandro Scardina, DMD/Pietro Messina, MD

Pages: 511-515
PMID: 22532958

Objective: Systemic lupus erythematosus (SLE) is a serious multisystem disease with a variety of cutaneous and oral manifestations. It is an autoimmune disorder whereby patients develop autoantibodies to many of their cells, cell components, and tissue. The microvascular changes in SLE play a role in the pathogenesis of this disease. The aim of this study was to investigate the gingival microcirculation in SLE patients. Method and Materials: Fifteen SLE patients and 15 healthy subjects were recruited for this study. Gingival microcirculation was investigated using videocapillaroscopy, a noninvasive technique that permits the in vivo evaluation of microvascular patterns. Results: Significant differences between patients and controls for the capillary density were seen. An increase of mean capillary density was observed in SLE patients (105.5 3.41) (P < .05). Conclusion: This study showed significant modifications of gingival microcirculation in SLE patients. (Quintessence Int 2012;43:511515)

Key words: capillaroscopy, gingival disease, microcirculation, systemic lupus erythematosus

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