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Volume 31 , Issue 4
July/August 2011

Pages 383-388

Lateral Ridge Augmentation Using an Equine Flex Bone Block Infused with Recombinant Human Platelet-Derived Growth Factor BB: A Clinical and Histologic Study

Nicola De Angelis, DDS, MSc/Michele Scivetti, DDS

PMID: 21837304
DOI: 10.11607/prd.00.0986

This paper reports on a patient who underwent horizontal ridge augmentation using recombinant human platelet-derived growth factor BB (rhPDGF-BB) in combination with a collagenate equine block. Ninety days after the first surgery, 8 mm of new bone was noted on a computed tomography scan, and three 5-mm implants were placed. Histology, performed using confocal laser scanning microscopy, showed a large amount of newly formed bone well characterized with osteon and resorption lacunae, which demonstrated the intense bone remodeling. This study supports the use of rhPDGF-BB in combination with allograft blocks. (Int J Periodontics Restorative Dent 2011;31:383388.)

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