Back

Volume 15 , Issue 2
March/April 1995
Pages 204-213

Clinical and histologic observation of replacement of biphasic calcium phosphate by bone tissue in monkeys

Hashimoto-Uoshima/Ishikawa/Kinoshita/Weng/Oda

PMID: 8593983
DOI: 10.11607/prd.00.0119

Biphasic calcium phosphate, consisting of B-tricalcium phosphate and hydroxyapatite, was implanted in wide and deep periodontal osseous defects of monkeys in combinatoin with the guided tissue regeneration technique. After 12 weeks, sites treated with a combination of biphasic calcium phosphate and guided tissue regeneration maintained the shape of the ridgem but both guided tissue regeneration and control sites (untreated) showed extreme resorption. A histopathologic investigation revealed that numerous machrophages contained small particles of ceramic within their vesicles and that active bone replacement occurred from the surrounding bone. Biphasic calcium phosphate has osteoconductive potential and this potential may be related to degradation by macrophage phagocytosis.

Full Text PDF File | Order Article

 

 

Adobe Acrobat Reader is required to view PDF files. This is a free program available from the Adobe web site.
Follow the download directions on the Adobe web site to get your copy of Adobe Acrobat Reader.