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Volume 20 , Issue 4
July/August 2000

Pages 399-411

Improved Bone Regeneration and Root Coverage Using a Resorbable Membrane with Physically Assisted Cell Migration and DFDBA

John R. Dodge, DMD, MS/Henry Greenwell, DMD, MSD/Connie Drisko, DDS/John W. Wittwer, DDS, MS/John Yancey, PhD/George Rebitski, BS

PMID: 11203580
DOI: 10.11607/prd.00.0371

Twelve patients with 2 Miller Class I or II buccal recession defects measuring = 3.0 mm were treated using the principles of guided tissue regeneration and followed for 12 months. The effectiveness of a polylactide (Guidor) resorbable membrane (GA sites) was compared to a combination treatment of polylactide membrane plus polyglactin root-lining mesh (Vicryl) and demineralized freeze-dried bone allograft (DFDBA) (GVB sites) designed to enhance cell migration and bone regeneration. There was 90% mean soft tissue root coverage for the GVB sites and 78% for the GA sites. The mean osseous dehiscence area coverage with hard tissue was 75% for GVB sites and 30% for GA sites.

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