Follow Us      

Share Page:

Volume 20 , Issue 1
January/February 2000

Pages 61-69

The Use of Demineralized Freeze-Dried Bone/Glycoprotein Matrix Grafts in Treating Baboon Periodontal Infrabony Defects

Neil M. Blumenthal, DDS, MS/Mario E. A. F. Alves, DDS, MS, DSc

PMID: 11203550
DOI: 10.11607/prd.00.0351

In an effort to improve regenerative capacity and establish higher levels of predictability, the use of a new graft material was investigated in baboon infrabony periodontal defects. A graft matrix composed of human demineralized freeze-dried bone combined with human connective tissue glycoprotein was implanted in 20 defects in 9 baboons. Control, debrided-only sites in the same animal served as a comparison. Grafted sites achieved a 1.8-mm greater reduction in probing depth and attachment gain compared to controls. In addition, 25.3% greater defect fill was found in grafted sites. Histologic analyses provided evidence of bone induction by the graft matrix and regeneration of new cementum, periodontal ligament, and bone in the grafted sites.

Full Text PDF File | Order Article


Get Adobe Reader
Adobe Acrobat Reader is required to view PDF files. This is a free program available from the Adobe web site.
Follow the download directions on the Adobe web site to get your copy of Adobe Acrobat Reader.


© 2015 Quintessence Publishing Co, Inc

PRD Home
Current Issue
Ahead of Print
Author Guidelines
Accepted Manuscripts
Submission Form
Quintessence Home
Terms of Use
Privacy Policy
About Us
Contact Us