Follow Us      


   Offical Journal of The Academy of Osseointegration

Share Page:

Volume 29 , Issue 5
September/October 2009

Pages 549-555

Time Sequence of Bone Healing Around Two Implant Systems in Minipigs: Preliminary Histologic Results

Daniela Carmagnola, DDS, PhD/Silvio Abati, MD, DDS/Alessandro Addis, DVM/Giovanni Ferrieri, MD, DMD/Matteo Chiapasco, MD/Eugenio Romeo, MD, DMD/Giorgio Vogel

PMID: 19888499
DOI: 10.11607/prd.00.0878

The aim of this study was to evaluate the early phases of bone healing around two different implant surfaces. For this purpose, four minipigs were used. Implants with rough titanium surfaces (ITI sandblasted/acid-etched and Brånemark TiUnite) were placed in the maxillae of the animals and sacrifice was scheduled in such a way that healing times of 3 days, 1 week, 2 weeks, 3 weeks, 4 weeks, 5 weeks, 6 weeks, and 7 weeks were obtained. Histologic analysis revealed that a similar pattern was observed in the phases of bone healing around both types of implants between 3 days and 7 weeks. This pattern consisted of the replacement of blood clot and bone debris with a provisional connective tissue in the first few weeks and with mineralized tissue and marrow spaces later on. Both rough surfaces allowed for “contact osteo­genesis” to take place. (Int J Periodontics Restorative Dent 2009;29:549–555.)

Full Text PDF File | Order Article


Get Adobe Reader
Adobe Acrobat Reader is required to view PDF files. This is a free program available from the Adobe web site.
Follow the download directions on the Adobe web site to get your copy of Adobe Acrobat Reader.


© 2020 Quintessence Publishing Co, Inc

PRD Home
Current Issue
Ahead of Print
Author Guidelines
Submission Form
Quintessence Home
Terms of Use
Privacy Policy
About Us
Contact Us