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Volume 28 , Issue 3
May/June 2008
Pages 265-271

Efficacy of Guided Tissue Regeneration in the Management of Through-and-Through Lesions Following Surgical Endodontics: A Preliminary Study

Silvio Taschieri, MD, DDS/Massimo Del Fabbro, BSc, PhD/ Tiziano Testori, MD, DDS/Massimo Saita, DDS/Roberto Weinstein, MD, DDS

PMID: 18605602

The purpose of this prospective study was to assess the outcome of periradicular surgery with or without guided tissue regeneration (GTR) for the treatment of through-and-through lesions. Thirty-four teeth were included according to specific selection criteria. In the test group (using GTR), after root-end filling, the defects were filled with anorganic bovine bone and covered with a resorbable collagen membrane. Healing was assessed according to specific criteria and graded as successful, doubtful, or failed. In the control group, neither grafts nor membranes were used. After 1 year, 31 teeth were evaluated. Of these, 22 (71%) healed successfully, 6 (19%) showed doubtful healing, and 2 were recorded as failures. The outcomes of the defects treated with GTR (88% successful) were significantly better than those of the control group (57% successful). The present study showed that the use of GTR associated with anorganic bovine bone in the treatment of through-and-through lesions may positively affect the healing process. (Int J Periodontics Restorative Dent 2008;28:265–271)

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