Follow Us      

LOGIN
 
Share Page:
Back

Volume 27 , Issue 4
July/August 2007

Pages 341-347


Histologic Analysis of the Acellular Dermal Matrix Graft Incorporation Process: A Pilot Study in Dogs

Sonia M. Luczyszyn, DDS, DSc / Marcio F. M. Grisi, DDS, DSc / Arthur B. Novaes Jr, DDS, DSc / Daniela B. Palioto, DDS, DSc / Sergio L. S. Souza, DDS, DSc / Mario Taba Jr, DDS, DSc


PMID: 17726990
DOI: 10.11607/prd.00.0758

Clinical results with acellular dermal matrix graft (ADMG) in periodontal surgeries suggest that the material is incorporated by the host tissues. However, histologic studies of the ADMG incorporation process are limited. The objective of this study was to evaluate the incorporation of ADMG into gingival tissues in a dog model. Gingival recession-type defects were created at the canines of six dogs. After 6 weeks, periodontal surgeries to repair the defects were performed using ADMG. Two animals each were sacrificed after 4, 8, and 12 weeks. At 4 weeks, thick collagen fibers from the ADMG were clearly seen in the connective tissue, and some blood vessels were penetrating into the ADMG. At 8 weeks, blood vessel penetration was enhanced, and collagen fiber bundles from the ADMG were seen sending branches into the connective tissue in all directions. After 12 weeks, the ADMG and the connective tissue seemed to be well integrated into a single highly vascularized structure, indicating almost complete incorporation of the ADMG. (Int J Periodontics Restorative Dent 2007;27:341347.)


Full Text PDF File | Order Article

 

 
Get Adobe Reader
Adobe Acrobat Reader is required to view PDF files. This is a free program available from the Adobe web site.
Follow the download directions on the Adobe web site to get your copy of Adobe Acrobat Reader.

 

© 2014 Quintessence Publishing Co, Inc

PRD Home
Current Issue
Ahead of Print
Archive
Author Guidelines
About
Accepted Manuscripts
Submission Form
Submit
Reprints
Permission
Advertising
Quintessence Home
Terms of Use
Privacy Policy
About Us
Contact Us
Help