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Volume 39 , Issue 3
May/June 2019

Pages 341347


Clinical and Histologic Evaluations of Porcine-Derived Collagen Matrix Membrane Used for Vertical Soft Tissue Augmentation: A Case Series

Algirdas Puisys, DDS, Spec Perio, PhD/Saulius Zukauskas, DDS/Ricardas Kubilius, DDS, PhD/Mike Barbeck, PhD/Dainius Razukevičius, DDS, PhD/Laura Linkevičiene, DDS, PhD/Tomas Linkevičius, DDS, Dip Pros, PhD


PMID: 30986283
DOI: 10.11607/prd.4097

This case series aimed to clinically and histologically evaluate porcine-derived membrane used for vertical thickening of thin soft tissues. Twenty porcine-derived collagen membranes and bone-level implants were placed in 20 patients. After 2 months, thickened soft tissues were measured and biopsy samples were harvested. All xenografts healed successfully. The average thickness of thin soft tissue before vertical thickening was 1.65 0.36 mm, while tissue thickness increased to 3.45 0.52 mm after the procedure (P < .001); the mean thickness increase was 1.8 0.13 mm. Histologic analysis showed complete integration of the graft and no differences (P = .4578) in vascularization between the host (39.74 17.15 vessels/mm2) and graft (30.43 11.26 vessels/mm2). It can be concluded that porcine-derived membrane can be used for vertical soft tissue thickening with substantial gain in tissue height.


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