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   Offical Journal of The Academy of Osseointegration

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Volume 35 , Issue 4
July/August 2015

Pages 463471

Membranes and Bone Substitutes in a One-Stage Procedure for Horizontal Bone Augmentation: A Histologic Double-Blind Parallel Randomized Controlled Trial

Mauro Merli, DDS/Marco Moscatelli, DDS/Giorgia Mariotti, DDS/Umberto Pagliaro, MD, DDS/Lorenzo Breschi, DDS, PhD/Annalisa Mazzoni, PhD/Michele Nieri, DDS, BSc

PMID: 26133135
DOI: 10.11607/prd.2418

The aim of this histologic, double-blind, parallel, randomized controlled trial was to compare anorganic bone mineral-collagen membranes (BB) and betatricalcium phosphate-pericardium collagen membranes (CJ) in a one-stage procedure for horizontal bone augmentation. A biopsy was performed in the regenerated area at abutment connection 6 months after surgery. Five patients were assigned and treated with the BB combination and five patients were treated with the CJ combination. At abutment connection, 6 months after grafting, no significant differences were evident in the histomorphometric comparisons, even if the percentage of residual graft, using the marrow spaces and soft tissue as a reference, tended to be greater in the CJ group (P = .0759).

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