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Volume 34 , Issue 1
January/February 2014

Pages e18e25


The Osseointegration Properties of Titanium Implants with Hydroxyapatite Submicron-Scale Features in the Rabbit Tibia


Young-Taeg Sul, DDS, PhD/Ross Towse, BS ChE, MBA


PMID: 24396849
DOI: 10.11607/prd.1685

The objective of this study was to biomechanically and histologically assess the stability and integration of titanium implants that include hydroxyapatite based submicron-scale features. Thirty-four 3.4 mm 6.5 mm implants, equally split between test (grit blasted, etched, and submicron scale deposition) and control (grit blasted and etched) groups, were placed in the tibiae of New Zealand White rabbits. At 3-weeks follow-up, the group with the submicron deposition showed significantly improved bone response compared with the control group. The test group required higher removal torque values, with its post-torque histology demonstrating both enhanced bone formation and an intact interface indicative of a robust bone-to-implant bond. (Int J Periodontics Restorative Dent 2013;33:e18e25. doi: 10.11607/prd.1685)


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