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Human Autopsy Study of Peri-implant Dehiscence Defects with Guided Bone Regeneration: A Case Report

Jae-Kook Cha, DDS, PhD/Mariano Sanz, DDS, PhD/Ui-Won Jung, DDS, PhD


PMID: 29897350
DOI: 10.11607/prd.3329

This report presents a histologic assessment of guided bone regeneration for dehiscence defects treated with bovine bone mineral or a combination of autogenous and synthetic bone. The samples were obtained from an autopsy specimen donated by a patient, which is a rare opportunity to evaluate long-term results of guided bone regeneration and osseointegration. The values for bone-to-implant contact were similar in both sites. The augmentation with bovine bone mineral demonstrated bone reconstruction after 1 year, whereas the augmentation with autogenous and synthetic bone failed to maintain the augmented volume, eventually leading to mucosal recession after 5.5 years.


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