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   Offical Journal of The Academy of Osseointegration

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Volume 18 , Issue 5
September/October 1998

Pages 503-513

New Attachment Achieved by Guided Tissue Regeneration Using a Bioresorbable Polylactic Acid Membrane in Dogs

Sallum/Sallum/Nociti, Jr/ Marcantonio/de Toledo

PMID: 10093526
DOI: 10.11607/prd.00.0286

Created periodontal defects in dogs were randomly assigned for experimental (Guidor bioresorbable membranes) or control (conventional therapy) treatment. The results showed t hat the new connective tissue attachment was significantly greater in test sites than in controls. This new attachment averaged 2.79 +- 0.74 mm and 1.47 +- 0.20 mm at test and control sites, respectively (P < 0.05). Epithelial downgrowth was also reduced in the test sites (P < 0.05). No differences in bone response were found. The bioresorbable barrier was effective in blocking gingival epithelial downgrowth and connective tissue proliferation, promoting new attachment according to the principles of guided tissue regeneration.

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