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Volume 35 , Issue 1
January/February 2015

Pages 105-114


Clinical Evaluation of Autologous Platelet-Rich Fibrin in the Treatment of Multiple Adjacent Gingival Recession Defects: A 12-Month Study

Mustafa Tunalı, DDS, PhD/Hakan Özdemir, DDS, PhD/Taner Arabacı, DDS, PhD/Bahadır Gürbüzer, DDS, PhD/M. Levent Pikdöken, DDS, PhD/Erhan Fıratlı, DDS, PhD


PMID: 25734713
DOI: 10.11607/prd.1826

Leukocyte- and platelet-rich fibrin (L-PRF) belongs to a new generation of platelet concentrates. There are limited numbers of studies focused on the use of L-PRF in gingival recession defects. This study evaluated the safety and effectiveness of using L-PRF membranes as a substitute for free connective tissue grafts (CTGs) as a treatment method for gingival recession defects. A total of 44 Miller Class I/II gingival recessions that were bilateral, adjacent, and greater than 3 mm in size were selected. Each recession site was randomly assigned to the test group (L-PRF) or the control group (CTG). After 12 months, root coverage was 76.63% and 77.36% in the L-PRF and CTG groups, respectively. It is suggested that L-PRF membrane may be an alternative graft material for treating multiple adjacent recessions greater than 3 mm in size without a requirement for additional surgery.


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