This case series explores the possibility of papilla regeneration for even the most severely compromised single-tooth implant sites. There is a clear presentation of the steps required to achieve adequate three-dimensional volume of hard and soft tissues to meet the biologic and esthetic goals. The sequencing and technical aspects of the therapy are presented with step-by-step photographic documentation. The limits of the treatment approach are also discussed. As esthetics is a driving factor in implant treatment, the ability to manage hard and soft tissue regeneration is paramount. This case series explores this issue for periodontally compromised patients.