Xeroderma pigmentosum (XP) is a very rare skin disorder where a person is highly sensitive to sunlight (photosensitive), has premature skin aging and is prone to developing skin cancers. Only Type B (XP, Cockayne syndrome) is associated with dental findings, which are namely dental caries, delayed eruption of teeth and malocclusion. To date, no case of XP with periodontal findings has been reported. Here we present a rare case of XP with oral and periodontal findings. The authors further hypothesised that periodontal destruction in XP patients is due to immune defects present in such patients. Keywords: bone loss, immunologic abnormalities, periodontitis, xeroderma pigmentosum