Share Page:

Volume 26 , Issue 2
March/April 2011

Pages 385–392

Healing of Ungrafted and Grafted Extraction Sockets After 12 Weeks: A Prospective Clinical Study

Susanne Heberer, DDS/Bassem Al-Chawaf, DDS/Carlo Jablonski, DMD/John J. Nelson, MD, MPH/Hermann Lage, MD, PhD/Katje Nelson, DDS, PhD

PMID: 21483892

Purpose: In this prospective study, bone formation in human extraction sockets augmented with Bio-Oss Collagen after a 12-week healing period was quantified and compared to bone formation in unaugmented extraction sockets. Materials and Methods: Selected patients with four-walled extraction sockets were included in this prospective study. After extraction, the sockets were randomly augmented using Bio-Oss Collagen or left to heal unfilled without raising a mucoperiosteal flap. At the time of implant placement, histologic specimens were obtained from the socket and analyzed. Statistical analysis was performed using the Wilcoxon signed-rank test. Results: Twenty-five patients with a total of 39 sockets (20 augmented, 19 unaugmented) were included in the study and the histologic specimens analyzed. All specimens were free of inflammatory cells. The mean overall new bone formation in the augmented sites was 25% (range, 8%–41%) and in the unaugmented sockets it was 44% (range, 3%–79%). There was a significant difference in the rate of new bone formation between the grafted and ungrafted sockets and a significant difference in the bone formation rate in the apical compared to the coronal regions of all sockets, independent of the healing mode. Conclusion: This descriptive study demonstrated that bone formation in Bio-Oss Collagen–grafted human extraction sockets was lower than bone formation in ungrafted sockets. Bone formation occurred in all specimens with varying degrees of maturation independent of the grafting material and was initiated from the apical region. Int J Oral Maxillofac Implants 2011;26:385–392

Key words: bone grafting, bovine bone mineral, collagen, extraction socket, socket preservation

Full Text PDF File | Order Article


Get Adobe Reader
Adobe Acrobat Reader is required to view PDF files. This is a free program available from the Adobe web site.
Follow the download directions on the Adobe web site to get your copy of Adobe Acrobat Reader.


© 2018 Quintessence Publishing Co, Inc JOMI Home
Current Issue
Ahead of Print
Author Guidelines
Submission Form
Quintessence Home
Terms of Use
Privacy Policy
About Us
Contact Us