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Volume 16 , Issue 6
November/December 2001

Pages 783–792

Quality Assessment of Randomized Controlled Trials of Oral Implants

Marco Esposito, DDS, PhD, Paul Coulthard, BDS, MFGDP, MDS, FDSRCS, PhD, Helen V. Worthington, BSc, MSc, PhD, FIS, Asbjørn Jokstad, DDS, PhD

PMID: 11769828

The aim of this study was to assess the quality of randomized controlled trials (RCTs) concerned with the effectiveness of oral implants and to create a trial register. A multilayered search strategy was used to identify all RCTs published by the end of 1999 in any language. The Cochrane Oral Health Group specialist register, PubMed, and personal libraries were searched. Seventy-four RCTs were identified. Forty-three articles, not presenting the same patient material, were independently assessed by 3 researchers using a specially designed form. A statistician assessed all trials for the appropriateness of statistics. The quality of each study was assessed on 7 items, including 3 key domains. Randomization and concealment allocation procedures were not described in 30 articles (70%). Reasons for withdrawals were not given in 10 reports(23%). No attempt at blinding was reported in 31 studies (72%). The quality of RCTs of oral implants is generally poor and needs to be improved. (INT J ORAL MAXILLOFAC IMPLANTS 2001;16:783–792)

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