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Volume 10 , Issue 6
November/December 1995

Pages 696-701

Increased Interleukin-1 in the Crevicular Fluid of Diseased Implants

Richard T. Kao, DDS, PhD/Donald A. Curtis, DMD/David W. Richards, DDS, PhD/ James Preble, DDS

PMID: 8530172

Diseased implants can be distinguished from healthy implants by the presence of inflammation in the surrounding tissue. Inflammation correlates with elevated levels of interleukin-1 in gingival crevicular fluid. An analysis of interleukin-1 levels in diseased implants compared to those in matching healthy implants in 12 patients indicates that the level of interleukin-1 was approximately three times that at healthy sites. Interleukin-1 levels may provide a means of monitoring the health status of dental implants. (INT J ORAL MAXILLOFAC IMPLANTS 1995;10:696701)

Key words: cytokines, implants, interleukin-1, peri-implantitis

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