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Volume 9 , Issue 1
January/February 1994
Pages 107-109

Phenytoin Hyperplasia Occurring in Relation to Titanium Implants: A Clinical Report

Winston W.L. Chee, BDS/Curtis E. Jansen, DDS

PMID: 8150508

Dilantin sodium is a commonly used anticonvulsive agent. A well-known side effect of this medication is hyperplasia of gingival tissues. This hyperplasia has also been reported in mucosa beneath complete dentures and has been related to poor oral hygiene. This case report describes hyperplasia of tissues around titanium implants in a patient taking Dilantin sodium to prevent epileptic seizures. The excess tissue was removed and hygiene reinforced. NO recurrence of the tissue enlargement is evident after 1 year.(INT J ORAL MAXILLOFAC IMPLANTS 1994;9:107—109.)

Key words: Dilantin, hyperplasia, implant

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