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Volume 8 , Issue 3
May/June 1993
Pages 309-315

Light and Confocal Laser Scanning Microscopic Evaluation of Hydroxyapatite Resorption Patterns in Medullary and Cortical Bone

Adriano Piattelli, MD/Gian Piero Cordioli, MD/Paolo Trisi, DDS/Piero Passi, MD/ Gian Antonio Favero, MD/Roland M. Meffert, DDS

PMID: 8225466

An animal study was conducted with unloaded blocks and hydroxyapatite (HA)-coated titanium implants. Four HA blocks were positioned in rabbit tibiae and four HA-coated titanium implants were positioned in pig tibiae. Implants were positioned so that half was placed in cortical bone and half in medullary space. Biopsy specimens were taken 4 months after implant placement for histologic evaluation. Light microscopy and confocal laser scanning microscopy demonstrated that the HA resorption rate was higher in the medullary spaces, whereas resorption was almost absent in the areas embedded in cortical bone. (INT J ORAL MAXILLOFAC IMPLANTS 1993;8:309—315.)

Key words: cortical bone, hydroxyapatite, medullary bone, resorption

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