LOGIN
 
Share Page:
Back

Volume 22 , Issue 3
May/June 2007

Pages 472–477


Surface-Etching Enhances Titanium Implant Osseointegration in Newly Formed (rhBMP-2–Induced) and Native Bone

Mohammed Qahash, DDS, MS / W. Ross Hardwick, MS, MMS, PA-C / Michael D. Rohrer, DDS, MS / John M. Wozney, PhD / Ulf M. E. Wikesjo, DDS, PhD


PMID: 17622015

Purpose: The influence of surface modifications on osseointegration in newly formed bone is not well established. The purpose of this study was to compare osseointegration at acid-etched versus turned implants in newly formed and native bone. Methods: Supra-alveolar peri-implant defects were created in 8 hound/Labrador mongrel dogs. Titanium implants 10 mm long (2 turned and 1 dual acid-etched) were placed 5 mm into the surgically reduced alveolar crest, creating 5-mm supra-alveolar peri-implant defects. Recombinant human bone morphogenetic protein-2 (rhBMP-2; 0.4 mg) in a collagen carrier was used to induce new bone formation. A macroporous, expanded polytetrafluoroethylene device was used to delineate new bone formation. The animals were euthanized at 8 weeks for histometric analysis of the experimental sites. Results: There were no significant differences in rhBMP-2induced bone density (mean plusmn SD) at acid-etched versus turned implants (20.6% plusmn 5.3% vs 23.8% plusmn 4.7%; P = .232). However, there was a significant difference in bone-implant contact in favor of the acid-etched implants (12.3% plusmn 6.8% vs 7.9% plusmn 3.1%; P = .05). Native bone density averaged 63.9% plusmn 7.5% and 64.5 plusmn 9.0% for acid-etched and turned implants, respectively (P = .641). Nevertheless, bone-implant contact was significantly enhanced at acid-etched versus turned implants (59.7% plusmn 11.3% vs 40.7% plusmn 21.2%; P = .005). Conclusions: Surface dual acid-etching of titanium implants has a positive effect on osseointegration in newly formed and native bone. Significant differences in bone density do not appear to influence this effect. Int J Oral Maxillofac Implants 2007;22:472–477

Key words: bone, e-PTFE, osseointegration, rhBMP-2, tissue engineering, titanium implants


Full Text PDF File | Order Article

 

 
Get Adobe Reader
Adobe Acrobat Reader is required to view PDF files. This is a free program available from the Adobe web site.
Follow the download directions on the Adobe web site to get your copy of Adobe Acrobat Reader.

 

© 2014 Quintessence Publishing Co, Inc JOMI Home
Current Issue
Ahead of Print
Archive
Author Guidelines
About
Accepted Manuscripts
Submission Form
Submit
Reprints
Permission
Advertising
Quintessence Home
Terms of Use
Privacy Policy
About Us
Contact Us
Help