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Volume 21 , Issue 1
January/February 2006

Pages 124–130


Langerhans’ Cell Histiocytosis: A Case Report of an Eosinophilic Granuloma of the Mandible Treated with Bone Graft Surgery and Endosseous Titanium Implants

Ludovico Sbordone, MD, DDS / Franco Guidetti, MD / Giovanni Battista Menchini Fabris, DDS / Carolina Sbordone


PMID: 16519191

Eosinophilic granuloma is the localized and most benign form of Langerhans’ cell histiocytosis. The disease shows a particular predilection for the head and neck region and usually involves the skull bones, where it manifests as well-defined lytic lesions on standard radiographs. The case of an extensive lesion involving the body of the mandible in a 52-year-old man is reported. Operative procedures consisted of enucleation of the lytic lesion and follow-up with clinical examinations and computerized tomographic studies of the mandible at 2, 12, and 18 months postoperatively. Reconstructive surgery without radiotherapy was performed with an autologous bone graft from the iliac crest and implant placement to provide support for a dental restoration.
Int J Oral Maxillofac Implants 2006;21:124–130

Key words: bone grafting, dental implants, eosinophilic granuloma, Langerhans’ cell histiocytosis


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