Share Page:

Volume 20 , Issue 6
November/December 2005

Pages 898–904

Bone Mineral Density and Bone Histomorphometry are Statistically Related

Marzio Todisco, DDS/Paolo Trisi, DDS, PhD

PMID: 16392347

Purpose: The aim of this study was to evaluate how closely analysis of bone quality performed using the bone mineral density (BMD) values obtained by quantitative computerized tomography (QCT) reflected the histologic bone density. Materials and Methods: Eighteen patients requiring implant therapy underwent CT scanning. Their data were processed using Image Master software, and the BMD was calculated by measuring the Hounsfield units and relating those values to a phantom (Calibration Phantom, Quantitative Technologies). Each patient wore a radiographic-surgical template in which titanium cylinders were placed as a drilling guide for preparation of the implant site. The mouth regions where the titanium guides were placed (on the CT images and in the patient’s mouth) corresponded to the implant sites where the BMD was measured and where tissue specimens for histomorphometric analysis retrieved. Forty specimens measuring 6 mm in length and 2 mm in diameter were obtained. Histomorphometric analysis was performed by digitizing the images, which were subsequently analyzed using the image analysis software IAS 2000. The bone volume (BV) was calculated as a percentage by dividing the area occupied by the mineralized bone over the entire microscopic field. Results: The results of the statistical analysis showed a Pearson correlation coefficient of 0.691 between the BV and BMD values, with a P value < 0.01, which was considered significant. Discussion and Conclusion: The results of this study support the use of QCT to assess the bone quality before implant placement to improve the planning of implant treatment. Int J Oral Maxillofac Implants 2005;20:898–904
Key words: bone density, computerized tomography, histomorphometry

Full Text PDF File | Order Article


Get Adobe Reader
Adobe Acrobat Reader is required to view PDF files. This is a free program available from the Adobe web site.
Follow the download directions on the Adobe web site to get your copy of Adobe Acrobat Reader.


© 2017 Quintessence Publishing Co, Inc JOMI Home
Current Issue
Ahead of Print
Author Guidelines
Accepted Manuscripts
Submission Form
Quintessence Home
Terms of Use
Privacy Policy
About Us
Contact Us