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Volume 13 , Issue 3
May/June 1998

Pages 333341

Implants Placed in Immediate Extraction Sites: A Report of Histologic and Histometric Analyses of Human Biopsies

Thomas G. Wilson, Jr, DDS, Robert Schenk, MD, Prof Dr Med, Daniel Buser, DMD, Prof Dr Med Dent, David Cochran, DDS, PhD, MS, MMSci

PMID: 9638003

Five titanium plasma-sprayed implants were biopsied from a human volunteer 6 months after placement. Four test implants had been placed in immediate extraction sockets, while one implant was placed in a mature site and served as a control. The histologic analysis demonstrated that all five implants achieved osseointegration as demonstrated by light microscopy, whereas a varying degree of bone-implant contact was observed. The nonloaded control implant had the highest percentage of bone-implant contact, 72%, followed by the two implants placed in the canine sites presenting with a horizontal defect dimension of 1.5 mm or less. These implants were placed without a barrier membrane, but in a submerged fashion. The histometric analysis showed a mean bone-implant contact of 50% for these two implants. The lowest mean bone-implant contact (17%) was observed for the two molar implants, which had horizontal defect dimensions of 4 mm; these implants were placed in a nonsubmerged fashion with the implants perforating an expanded polytetrafluoroethylene membrane. The authors concluded that osseointegration may occur in immediate extraction sites in humans using titanium implants with a plasma-sprayed surface. The horizontal component of the peri-implant defect was apparently the most critical factor relating to the final amount of bone-implant contact. (INT J ORAL MAXILLOFAC IMPLANTS 1998;13:333341) Key words: bone-implant contact, human biopsy, immediate extraction sites, osseointegration, titanium plasma-sprayed implants

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