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Volume 32 , Issue 1
January/February 2017

Pages e47e54


Mechanism and Clinical Properties of StemBios Cell Therapy: Induction of Early Osseointegration in Novel Dental Implants


Chao-Chia Weng, DDS/Keng-Liang Ou, PhD/Chia-Yu Wu, DDS/Yen-Heng Huang, DDS/James Wang, PhD/Yun Yen, PhD/Han-Yi Cheng, PhD/Yun-Ho Lin, DDS


PMID: 28095525
DOI: 10.11607/jomi.4460

Purpose: To examine early bone tissue healing in dental implants incorporating StemBios cell therapy. Materials and Methods: SLAffinity samples were examined by scanning electron microscopy and atomic force microscopy. The clinical trial comprised 11 patients, who each received a dental implant in the mandible. Only one of these 11 patients received StemBios cell therapy in combination with the dental implant. The patients continued to be observed over a 4-month period after implantation using computed tomography and resonance frequency analysis. Results: It was found that StemBios cell therapy promoted bone tissue healing in the case of the treated dental implant. The data indicated that stress altered more smoothly and declined faster in the patient who received the StemBios cell therapy than those without StemBios cell therapy over 4 months. Conclusion: A dental implant with SLAffinity surface treatment, in combination with StemBios cell therapy, significantly promoted bone tissue healing, especially at early osseointegration compared with that of implants without StemBios cell therapy when monitored over a 4-month period.


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