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Volume 29 , Issue 5
September/October 2014

Pages 11981203

Recombinant Human Bone Morphogenetic Protein 2 in Augmentation Procedures: Case Reports

Jaques Luiz, DDS, MSc/Luis Eduardo Marques Padovan, DDS, MSc, PhD/Marcela Claudino, DDS, MSc, PhD

PMID: 25216148
DOI: 10.11607/jomi.3543

To successfully rehabilitate edentulous patients using endosseous implants, there must be enough available bone. Several techniques have been proposed for augmentation of sites with insufficient bone volume. Although autogenous bone has long been considered the gold standard for such procedures, the limited availability of graft material and a high morbidity rate are potential disadvantages of this type of graft. An alternative is to use recombinant human bone morphogenetic protein 2 (rhBMP-2), which is able to support bone regeneration in the oral environment. These cases demonstrate the applicability of rhBMP-2 in maxillary sinus elevation and augmentation procedures in the maxilla to enable dental implant placement. The use of rhBMP-2 in alveolar augmentation procedures had several clinical benefits for these patients.

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