LOGIN
 
Share Page:
Back

Volume 28 , Issue 5
September/October 2013

Pages e252e259


Effects of Implant Surface on Bone Healing Around Titanium Screw Implants in Ovariectomized Rats


Hideo Tateishi, DDS/Yasuhiro Okamoto, DDS/Kazuhiko Kinoshita, DDS, PhD/Hideharu Hibi, DDS, PhD/Minoru Ueda, DDS, PhD


PMID: 24066342
DOI: 10.11607/jomi.te05

Purpose: The aim of this study was to investigate whether estrogen deficiency interrupts bone healing around titanium implants and to evaluate whether bone healing around implants under a condition of estrogen deficiency is affected by variations in implant surface characteristics. Materials and Methods: Forty-eight female rats were divided into two groups: ovariectomized rats (OVX; n = 24) and sham-operated rats (SHAM; n = 24). Each group was further divided into two groups: a machine-polished implants group and a sandblasted implants group. One implant was placed into the left femur of each rat 84 days after OVX or sham surgery. After 28 or 56 days, the rats were killed, and nondecalcified sections were obtained. Bone-to-implant contact (BIC) and bone area (BA) around the implants were assessed for cortical and cancellous bone. Furthermore, bone density (BD) was evaluated in a 500-mm-wide zone of cancellous bone lateral to the implants. Results: At 28 and 56 days after implantation, no significant differences were found between the OVX and SHAM groups for BIC and BA in cortical bone. BIC, BA, and BD with cancellous bone were lower in the OVX group than in the SHAM group. However, BIC and BA tended to increase with the sandblasted implant surface. Conclusions: Estrogen deficiency affected bone healing and bone density around titanium implants, especially in cancellous bone, but the sandblasted surface has the possibility to improve osseointegration. However, the positive effect of this rough surface is limited at the implant surface.


Full Text PDF File | Order Article

 

 
Get Adobe Reader
Adobe Acrobat Reader is required to view PDF files. This is a free program available from the Adobe web site.
Follow the download directions on the Adobe web site to get your copy of Adobe Acrobat Reader.

 

© 2014 Quintessence Publishing Co, Inc JOMI Home
Current Issue
Ahead of Print
Archive
Author Guidelines
About
Accepted Manuscripts
Submission Form
Submit
Reprints
Permission
Advertising
Quintessence Home
Terms of Use
Privacy Policy
About Us
Contact Us
Help