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Volume 27 , Issue 6
November/December 2012

Pages 1541–1546


The Influence of Substitute Materials on Bone Density After Maxillary Sinus Augmentation: A Microcomputed Tomography Study

Sebastian Kühl, Dr Med Dent/Hermann Götz, Dipl-Phys/Christoph Brochhausen, Dr Med/Norbert Jakse, Prof Dr Med, Dr Med Dent/Andreas Filippi, Prof Dr Med Dent/Bernd d’Hoedt, Prof Dr Med Dent/Matthias Kreisler, Prof Dr Med Dent


PMID: 23189308

Purpose: To evaluate whether adding bone substitute materials to autogenous particulated bone (PAB) might have an effect on the density of the grafted bone after maxillary sinus augmentation. Materials and Methods: Thirty healthy patients undergoing lateral antrostomy were included. Sinuses were augmented at random with PAB (n = 10) (control group); a mixture of PAB and beta-tricalcium phosphate (β-TCP) (n = 10) (experimental group); or a mixture of PAB, β-TCP, and hydroxyapatite (HA) (n = 10) (experimental group). A sample of each graft material was obtained at time of maxillary sinus augmentation, and microcomputed tomography (μ-CT) analyses were performed. Five months later, samples of the augmented areas (n = 23) were harvested by means of a trephine bur, and μ-CT analyses of these samples were performed. Density values for the bone were compared to the data obtained 5 months before from the original material. Results: All groups showed increasing density values after a healing time of 5 months. Because of a high dropout rate, the sample size was too small to compare the groups statistically. Conclusions: Bone density increased after maxillary sinus augmentation for both PAB alone or in combination with substitute materials based on HA and/or β-TCP particles. A larger sample size and a split-mouth design would help to reliably reveal significant differences between the single materials. Int J Oral Maxillofac Implants 2012;27:1541–1546

Key words: bone mineral density, bone replacement materials, maxillary sinus floor augmentation, microcomputed tomography


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