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Oral Health & Preventive Dentistry

Edited by Prof. Dr. Jean-François Roulet, Prof. Dr. Dr. Niklaus P. Lang, Prof. Dr. Palle Holmstrup

Official journal of the Academy of Minimally Invasive Dentistry, the World Congress of Microdentistry, and the European Society of Preventive Dentistry

ISSN (print) 1602-1622 • ISSN (online) 1757-9996


Spring 2004
Volume 2 , Issue 1

Pages: 49-58
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A Systematic Review of the Effectiveness of Anticalculus Dentifrices

Netuveli, Gopalakrishnan S. / Sheiham, Aubrey

To assess the evidence on the effectiveness of commercially available anticalculus dentifrices. Systematic search for published and unpublished epidemiological data in 7 electronic databases, 5 journals, and the bibliographies of retrieved papers and by making contact with subject experts in this field. Thirty-two reports were identified containing comparisons of one or more active agents with a placebo dentifrice and calculus measured using the Volpe-Manhold Index (VMI). Random effect model for 3-month studies showed an effect size of 0.6 for all comparisons. The effect sizes varied from 0.3 for dentifrices with zinc chloride 0.5% to 1.1 for pyrophosphate 1.3% and copolymer 1.5% dentifrices. Meta-analysis of all the studies with 6-month follow-up gave an effect size of 1.1 (1.5 to 0.8) and for 12-month follow-up the effect size was 13.6 (21.4 to 5.8). Anticalculus dentifrices containing pyrophosphates, zinc compounds and/or co-polymers were effective in significantly reducing calculus scores (VMI).

Keywords: calculus, anti-calculus, dentifrices, pyrophosphate, zinc citrate, co-polymer, toothpaste, systematic review

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