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Oral Health & Preventive Dentistry

Edited by Prof. Dr. Jean-François Roulet, Prof. Dr. Dr. Niklaus P. Lang, Prof. Dr. Palle Holmstrup

Official journal of the Academy of Minimally Invasive Dentistry, the World Congress of Microdentistry, and the European Society of Preventive Dentistry

ISSN (print) 1602-1622 • ISSN (online) 1757-9996


Winter 2006
Volume 4 , Issue 4

Pages: 255-263
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Remineralisation of Carious Enamel Lesions after Application of a CHX/F-Mouthrinse Compared with Sole CHX- and Placebo-Application

Altenburger, Markus Jörg / Klasser, Manfred / Schirrmeister, Jörg Fabian / Hellwig, Elmar

Purpose: The purpose of this cross-over, double-blind, placebo-controlled, randomised in situ study was to evaluate the remineralisation of demineralised enamel specimens using a CHX/NaF mouthrinse in comparison with a CHX- and a placebomouthrinse. Materials and Methods: Twenty-four volunteers received intraoral appliances with mounted demineralised enamel specimens. They rinsed their mouths twice a day (10 ml for 1 minute) with the respective preparation. After 14 days, the in situ mineral gain and fluoride uptake were determined. Results: Mineral gain was significantly higher after using CHX/F mouthrinse (358.4 ± 372.1 Vol.%·μm) compared with CHX (95.6 ± 192.2 Vol.%·μm) and placebo treatment (80.8 ± 159.6 Vol.%·μm). Moreover, CHX/F treatment (2751.1 ± 1494.9 μg/cm3) resulted in a significantly higher fluoride uptake compared with CHX- (83.8 ± 94.0 μg/cm3) and placebo- (136.6 ± 137.3 μg/cm3) mouthrinses. Conclusion: The in situ study approves that using a CHX/F mouthrinse supports the remineralisation of initial carious lesions.

Keywords: caries, chlorhexidine, enamel, mouthrinse

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