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Oral Health & Preventive Dentistry

Edited by Prof. Dr. Jean-François Roulet, Prof. Dr. Dr. Niklaus P. Lang, Prof. Dr. Palle Holmstrup

Official journal of the Academy of Minimally Invasive Dentistry, the World Congress of Microdentistry, and the European Society of Preventive Dentistry

ISSN (print) 1602-1622 • ISSN (online) 1757-9996


Fall 2007
Volume 5 , Issue 3

Pages: 235-244
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Oral Health and Pro-inflammatory Status in End-stage Renal Disease Patients

Buhlin, Kare / Bárány, Peter / Heimbürger, Olof / Stenvinkel, Peter / Gustafsson, Anders

Purpose: The aim of the present study was to investigate the oro-facial health of patients with end stage renal disease, focusing on their periodontal conditions. Material and Methods: A total of 51 patients (33 men) between the ages of 22 and 81 years with different types of chronic kidney disease that needed renal dialysis, underwent a full dental examination including a panoramic radiograph. A blood sample was collected from the subjects to investigate the levels of pro-inflammatory biomarkers. Results: A large proportion of patients had oral health problems. A total of 35% claimed that they suffered problems of the oral cavity and 51% had periapical osteitis around one or more teeth. A high number of patients also suffered from gingivitis (46%), severe periodontitis (35%) and 37% had cavities due to caries. On average the patients had 22.9 (SD 7.3) teeth and 14% had complete or partial dentures. Although periodontitis influenced the C-reactive protein level and oral pathology was significant within this specific population, the correlation between inflammatory biomarkers and dental parameters was weak. Conclusions: This study indicates that a substantial number of patients who suffer from advanced chronic kidney disease, close to the start of dialysis treatment, have dental problems that require attention.

Keywords: dialysis, kidney disease, oral health, periodontitis, risk factors

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