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Quintessence Publishing: Journals: OFPH
Journal of Oral & Facial Pain and Headache

Edited by Barry J. Sessle, BDS, MDS, BSc, PhD, FRSC

Official Journal of the American Academy of Orofacial Pain,
the European, Asian, and Ibero-Latin Academies of Craniomandibular
Disorders, and the Australian Academy of Orofacial Pain

ISSN 2333-0384 (print) • ISSN 2333-0376 (online)

Publication:
Fall 2011
Volume 25 , Issue 4

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Effectiveness of Low-Level Laser Therapy in Temporomandibular Disorders: A Systematic Review and Meta-Analysis

Ambra Petrucci, DDS/Fabrizio Sgolastra, DDS/Roberto Gatto, MD, DMD/Antonella Mattei, ScD/Annalisa Monaco, DDS

Pages: 298307
PMID: 22247925

Aim: To assess the scientific evidence on the efficacy of low-level laser therapy (LLLT) in the treatment of temporomandibular disorders (TMD). Methods: The databases of PubMed, Science Direct, Cochrane Clinical Trials Register, and PEDro were manually and electronically searched up to February 2010. Two independent reviewers screened, extracted, and assessed the quality of the publications. A meta-analysis- was performed to quantify the pooled effect of LLLT on pain and function in patients with chronic TMD. Results: The literature search identified 323 papers without overlap between selected databases, but after the two-phase study selection, only six randomized clinical trials (RCT) were included in the systematic review. The primary outcome of interest was the change in pain from baseline to endpoint. The pooled effect of LLLT on pain, measured through a visual analog scale with a mean difference of 7.77 mm (95% confidence interval [CI]: 2.49 to 18.02), was not statistically significant from placebo. Change from baseline to endpoint of secondary outcomes was 4.04 mm (95% CI 3.06 to 5.02) for mandibular maximum vertical opening; 1.64 mm (95% CI 0.10 to 3.17) for right lateral excursion and 1.90 mm (95% CI: 4.08 to 7.88) for left lateral excursion. Conclusion: Currently, there is no evidence to support the effectiveness of LLLT in the treatment of TMD. J Orofac Pain 2011;25:298307

Key words: laser, meta-analysis, systematic review, temporomandibular disorders, temporomandibular joint

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