Home Subscription Services

Journal of Oral & Facial Pain and Headache
OFPH Home Page
About the Editor
Editorial Board
Accepted Manuscripts
Author Guidelines
Submission Form
Reprints / Articles
Quintessence Publishing: Journals: OFPH
Journal of Oral & Facial Pain and Headache

Edited by Barry J. Sessle, BDS, MDS, BSc, PhD, FRSC

Official Journal of the American Academy of Orofacial Pain,
the European, Asian, and Ibero-Latin Academies of Craniomandibular
Disorders, and the Australian Academy of Orofacial Pain

ISSN 2333-0384 (print) • ISSN 2333-0376 (online)

Impact factor: 2.76

Spring 2011
Volume 25 , Issue 2

Share Abstract:

Changes in Regional Gray and White Matter Volume in Patients with Myofascial-type Temporomandibular Disorders: A Voxel-based Morphometry Study

Geoffrey Gerstner, DDS, MS, PhD/ Eric Ichesco, BS/ Andres Quintero, BDS/ Tobias Schmidt-Wilcke, MD

Pages: 99106
PMID: 21528116

Aims: To use magnetic resonance imaging (MRI) and voxel-based morphometry (VBM) to search for evidence of altered brain morphology in patients with temporomandibular disorders (TMD). Methods: Using VBM, regional gray and white matter volume was investigated in nine TMD patients and nine carefully matched healthy controls. Results: A decrease in gray matter volume occurred in the left anterior cingulate gyrus, in the right posterior cingulate gyrus, the right anterior insular cortex, left inferior frontal gyrus, as well as the superior temporal gyrus bilaterally in the TMD patients. Also, white matter analyses revealed decreases in regional white matter volume in the medial prefrontal cortex bilaterally in TMD patients. Conclusion: These data support previous findings by showing that TMD, like other chronic pain states, is associated with changes in brain morphology in brain regions known to be part of the central pain system. J OROFAC PAIN 2011;25:99106

Key words: anterior cingulate gyrus, central sensitization, chronic pain, neuroimaging, voxel-based morphometry

Full Text PDF File | Order Article


Get Adobe Reader
Adobe Acrobat Reader is required to view PDF files. This is a free program available from the Adobe web site.
Follow the download directions on the Adobe web site to get your copy of Adobe Acrobat Reader.
  © 2017 Quintessence Publishing Co Inc

Home | Subscription Services | Books | Journals | Multimedia | Events | Blog
Terms of Use | Privacy Policy | About Us | Contact Us | Advertising | Help | Sitemap | Catalog