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Quintessence Publishing: Journals: OFPH
Journal of Oral & Facial Pain and Headache

Edited by Barry J. Sessle, BDS, MDS, BSc, PhD, FRSC

Official Journal of the American Academy of Orofacial Pain,
the European, Asian, and Ibero-Latin Academies of Craniomandibular
Disorders, and the Australian Academy of Orofacial Pain

ISSN 2333-0384 (print) • ISSN 2333-0376 (online)

Spring 2002
Volume 16 , Issue 2

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Pressure-Pain Threshold Variation in Temporomandibular Disorder Myalgia over the Course of the Menstrual Cycle

Hans Isselée, RPT, Antoon De Laat, LDS, GHO, Bernard De Mot, DDS, PhD, Roeland Lysens, MD, PhD,

Pages: 105–117
PMID: 12043517

Aims: To evaluate the influence of the menstrual cycle on pressure-pain thresholds (PPTs) in patients with masticatory myalgia. Methods: Fluctuations in pain sensitivity during 2 consecutive menstrual cycles were assessed in 15 normally menstruating patients with a myogenous temporomandibular disorder (TMD). Muscle pain was measured by the use of pressure algometry and a visual analog scale (VAS). The McGill Pain Questionnaire was used to assess the sensory, affective, and evaluative dimensions of the pain. Results: Since 5 patients dropped out of the study due to pregnancy, unexpected menstrual cycle irregularities, or personal problems, statistical analysis was performed on 10 patients. Time had a significant influence on the pain condition. The PPTs of all muscle sites increased significantly and progressively over time by 16% to 42% in the follicular and luteal phases. PPTs remained low in the perimenstrual phase. The VAS pain rating did not correspond well with the PPTs, and the statistical analysis showed that the VAS ratings could not be used as predictors for the PPT measurements or detect the differences between cycle phases. The sensory, affective, and evaluative dimensions of the pain were significantly lower at the end of the trial. Conclusion: These data suggest a significant influence of the menstrual cycle on pain report and a nonspecific improvement of the chronic myogenous TMD. J OROFAC PAIN 2002;16:105–117.

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