Share Page:

Volume 31 , Issue 4
Fall 2017

Pages e29e36

Prevalence of Temporomandibular Disorders in Rheumatoid Arthritis and Associated Risk Factors: A Nationwide Study in Taiwan

Ching-Yueh Lin, MD/Chi-Hsiang Chung, PhD/Heng-Yi Chu, MD/Liang-Cheng Chen, MD, MS/Kuo-Hsien Tu, MD/Chang-Huei Tsao, PhD/Yung-Tsan Wu, MD/Wu-Chien Chien, PhD

PMID: 29073669
DOI: 10.11607/ofph.1917

Aims: To investigate the association between temporomandibular disorders (TMD) and rheumatoid arthritis (RA), as well as potential risk factors for TMD and the preventive effect of medications on TMD, by using the Taiwan National Health Insurance Research Database. Methods: In total, 17,317 patients newly diagnosed with RA and 17,317 matched controls without RA were followed up from 2000 to 2010. Cox regression was used to determine risk factors for developing TMD. Kaplan-Meier curve with log-rank test was used to determine the cumulative risk of TMD in RA patients and the effects of antirheumatic medications. Results: Cox regression showed a higher risk of developing TMD if patients had RA (adjusted hazard ratio [HR] 2.538, P < .001) and a lower risk if patients were of male gender and elderly (≥ 40 years) in comparison to younger patients (20 to 29 years) (P < .01). Patients with insomnia, stroke, and mental disorders had, respectively, 4.756, 6.929, and 9.671 times the number of events of TMD compared to those without diseases (P < .001). No patients with RA treated with disease-modifying antirheumatic drugs (DMARDs) developed TMD after the 11-year follow-up. Conclusion: RA patients had 2.538 times the events of TMD compared with non-RA patients during this trial in Taiwan. The other risk factors for developing TMD included female gender, younger age, insomnia, stroke, and mental disorders. The DMARDs had a beneficial effect on prevention of TMD.

Full Text PDF File | Order Article


Get Adobe Reader
Adobe Acrobat Reader is required to view PDF files. This is a free program available from the Adobe web site.
Follow the download directions on the Adobe web site to get your copy of Adobe Acrobat Reader.


© 2021 Quintessence Publishing Co, Inc

Current Issue
Ahead of Print
Author Guidelines
Submission Form
Quintessence Home
Terms of Use
Privacy Policy
About Us
Contact Us