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Quintessence Publishing: Journals: OFPH
Journal of Oral & Facial Pain and Headache

Edited by Barry J. Sessle, BDS, MDS, BSc, PhD, FRSC

Official Journal of the American Academy of Orofacial Pain,
the European, Asian, and Ibero-Latin Academies of Craniomandibular
Disorders, and the Australian Academy of Orofacial Pain

ISSN 2333-0384 (print) • ISSN 2333-0376 (online)

Publication:
Winter 2005
Volume 19 , Issue 1

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Mechanisms Associated with Unusual Orofacial Pain

Gilles Lavigne, DMD, MSc, PhD/Alain Woda, DDS, PhD/Edmond Truelove, DDS, MSc/Jonathan A. Ship, DMD, FRCS(Edin)/Thuan Dao, DMD, MSc, PhD, FRCD(c)/Jean-Paul Goulet, DDS, MSc, FRCD

Pages: 921
PMID: 15779535

This article presents an overview of possible mechanisms associated with pain perception, with a specific focus on understanding unusual manifestations of orofacial pain associated with nerve insult. It includes recent evidence concerning neurobiological changes that occur in the periphery at tissue and nerve sites, or within the central nervous system, and that may involve chemical and inflammatory responses, sensitization, or alterations of cellular function. Moreover, the contribution of the autonomic nervous system, changes in emotional reactivity and vigilance, the roles of high brain centers such as the basal ganglia (nigro-striatal) system, and the influence of aging and gender, are briefly described. J Orofac Pain 2005;19:921

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