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Quintessence Publishing: Journals: OCTE

 

Oral & Craniofacial Tissue Engineering

Edited by Ole T. Jensen, DDS, MS

Official Journal of the Tissue Engineering Society, the Chinese Society of Oral Biomedicine, and the Japanese Society of Regenerative Medicine

ISSN (print) 2158-3722 • ISSN (online) 2158-3706

Publication:
Oral & Craniofacial Tissue Engineering
Summer 2011
Volume 1 , Issue 2

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Biointegration of the Osteo-odonto Lamina in the Modified Osteo-odonto Keratoprosthesis: Engineering of Tissue to Restore Lost Vision

Yoh Sawatari, DDS/Robert E. Marx, DDS/Victor L. Perez, MD/Jean-Marie Parel, PhD

Pages: 112117

The modified osteo-odonto keratoprosthesis (MOOKP) is a biologic keratoprosthesis that is used to treat a severely scarred cornea. The procedure involves multiple stages, including the transplantation of buccal mucosa to the damaged ocular surface and the implantation of an osteo-odonto lamina with a mounted polymethylmethacrylate lens. Among the keratoprostheses currently available, the MOOKP has proven to be the most effective based on the number of patients who have undergone the procedure and the duration of documented follow-up. Upon successful biointegration of the osteo-odonto lamina, the keratoprosthesis is able to resist resorption, provide stability, and prevent bacterial invasion and epithelial ingrowth. The effectiveness of the MOOKP is dependent on the anatomic and physiologic characteristics of the dental tissues and periodontal ligament. Oral Craniofac Tissue Eng 2011;1:112117

Key Words: biointegration, keratoprosthesis, lamina, vision

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