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Oral & Craniofacial Tissue Engineering

Edited by Ole T. Jensen, DDS, MS

Official Journal of the Tissue Engineering Society, the Chinese Society of Oral Biomedicine, and the Japanese Society of Regenerative Medicine

ISSN (print) 2158-3722 • ISSN (online) 2158-3706

Oral & Craniofacial Tissue Engineering
Winter 2011
Volume 1 , Issue 4

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Somatic Stem Cell Biology and Periodontal Regeneration

Bin Zhu, DDS, PhD/Yihan Liu, DDS, PhD/Dehua Li, DDS, PhD/Yan Jin, DDS, PhD

Pages: 322–330

Somatic stem cells have been acknowledged for their ability to differentiate into multiple cell types and their capacity for self-renewal. Some mesenchymal stem cells play a dominant role in the repair and reconstruction of periodontal tissues. Both dental-derived and some non–dental-derived mesenchymal stem cells possess the capacity for periodontal regeneration under certain conditions with induced differentiation, proliferation, cellular secretion, and their interactions. Stem cell–based tissue engineering technology promises to bring improvements to periodontal regeneration, biologic tooth repair, and bioengineered implants. The present review discusses the roles and values of various somatic stem cells in periodontal regeneration. Oral Craniofac Tissue Eng 2011;1:322–330

Key words: mesenchymal stem cell, periodontal regeneration, somatic stem cell, tissue engineering

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